HIV (Human Immunodeficiency Virus) is a virus that attacks the immune machine and can lead to received immunodeficiency syndrome (AIDS). HIV can be transmitted through unprotected sexual contact, sharing needles or syringes, and from mother to child in the course of pregnancy, childbirth, or breastfeeding.
Since the discovery of HIV in the 1980s, vast development has been made in growing medicines that can assist manipulate the virus and its progression. In this article, we will talk about the current and brand new HIV/AIDS medicines reachable to patients.
Existing HIV/AIDS Medications
The first medicinal drugs used to deal with HIV had been nucleoside reverse transcriptase inhibitors (NRTIs). These drugs labored by means of preventing the virus from replicating itself. Some of the NRTIs nonetheless used these days include zidovudine (AZT), lamivudine (3TC), and tenofovir (TDF).
Another type of medicinal drug used to deal with HIV is non-nucleoside reverse transcriptase inhibitors (NNRTIs). These tablets work with the aid of binding to and altering the reverse transcriptase enzyme, which is accountable for replicating the virus. Some examples of NNRTIs consist of efavirenz (EFV), nevirapine (NVP), and etravirine (ETR).
Protease inhibitors (PIs) are every other class of HIV medications. They work via stopping the virus from assembling new copies of itself. Some examples of PIs encompass atazanavir (ATV), darunavir (DRV), and lopinavir/ritonavir (LPV/r).
Integrase inhibitors (INIs) are a more recent classification of HIV medications. They work via blockading the integrase enzyme, which is accountable for incorporating the virus's DNA into the host cell's DNA. Some examples of INIs include raltegravir (RAL), elvitegravir (EVG), and dolutegravir (DTG).
Combination therapies, or antiretroviral therapy (ART), are now the well-known cure for HIV. These healing procedures combine medicinal drugs from special classes to stop the virus from replicating and decrease the threat of developing drug resistance. Some examples of ART include tenofovir / emtricitabine / efavirenz (TDF/FTC/EFV), darunavir / cobicistat / emtricitabine / tenofovir alafenamide (DRV/c/FTC/TAF), and dolutegravir / rilpivirine (DTG/RPV).
Latest HIV/AIDS Medications
In latest years, numerous new medicinal drugs have been developed to deal with HIV. These medicinal drugs provide elevated efficacy and fewer side consequences in contrast to older treatments. Some of the modern-day HIV/AIDS medications include:
Biktarvy (bictegravir / emtricitabine / tenofovir alafenamide): Biktarvy is an aggregate therapy that was once authorized via the FDA in 2018. It consists of a new integrase inhibitor referred to as bictegravir, along with emtricitabine and tenofovir alafenamide. Biktarvy is a once-daily pill that is noticeably tremendous at suppressing the virus and has a low threat of drug resistance.
Trogarzo (ibalizumab): Trogarzo is a monoclonal antibody that used to be approved by the FDA in 2018. It is used in aggregate with different HIV medications in patients who have developed drug resistance to different treatments. Trogarzo is administered intravenously every two weeks and has been proven to be wonderful in reducing viral load in patients with multidrug-resistant HIV.
Tags:
Medications for HIV, AIDS HIV Medications, List of Medications for HIV, Medication for HIV and AIDS, AIDS Treatment Medicine, AIDS Medication Cost, New AIDS Medication, HIV Best Medicine, HIV Positive Medicine, Current HIV Medications, Medicine for HIV and AIDS
